National Chromatography Inco
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A Preparative NEUROSYIL Phenyl 100Å column is a type of high-performance liquid chromatography (HPLC) column used primarily for purification (not just analysis) of chemical compounds, especially in larger-scale separations.
Preparative Column: Designed for purifying milligrams to grams of material (vs. analytical columns that analyze micrograms to milligrams).
Phenyl: Refers to the stationary phase—phenyl-functionalized silica particles. The phenyl group interacts via:
π-π interactions
Hydrophobic interactions
Some polar selectivity
100Å (Angstroms): This is the pore size of the silica particles:
100 Å = 10 nm pores
Suitable for small to mid-sized organic molecules
Not ideal for very large biomolecules (like intact proteins or DNA)
