National Chromatography Inco
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Hi-Purit™ Diol SPE Cartridges are specialized Solid Phase Extraction (SPE) cartridges designed for sample preparation and purification in analytical chemistry. They use a diol-bonded silica as the sorbent material. Here are the main uses and applications of these cartridges:
Primary Uses of Hi-Purit™ Diol SPE Cartridges
1. Normal Phase Chromatography Applications
Diol-functionalized silica behaves similarly to unmodified silica but offers milder polarity, making it useful for normal-phase extraction.
It allows reproducible retention and elution of polar compounds.
2. Purification of Polar Compounds
Effective for retaining and purifying hydrophilic analytes, such as:
Carbohydrates
Glycosides
Peptides
Phenolic compounds
Flavonoids
3. Alternative to Silica or Aminopropyl Phases
Diol offers reduced hydrogen bonding compared to bare silica, providing more selective interactions.
Better suited for compounds sensitive to acidic silanol groups on silica.
4. Sample Clean-Up Prior to HPLC/GC/MS
Removes matrix interferences from biological, food, or environmental samples.
Prepares samples for downstream analytical techniques by reducing background noise and improving sensitivity.
