National Chromatography Inco
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Hi-Purit™ AL-N SPE Cartridges are a type of Solid Phase Extraction (SPE) cartridge designed primarily for analytical sample preparation, especially in environmental, pharmaceutical, and food testing labs. Here's a breakdown of their uses and purpose:
Primary Uses of Hi-Purit™ AL-N SPE Cartridges:
Extraction of Acidic Compounds:
The AL-N (commonly indicating alumina neutral) phase is typically used to retain acidic analytes while letting neutral and basic compounds pass through.
Useful in separating acidic components from complex matrices.
Cleanup of Organic Extracts:
Ideal for purifying organic solvents/extracts after initial extraction, removing interferences before analysis by LC-MS, GC-MS, or HPLC.
Environmental Sample Analysis:
Commonly used in EPA methods for testing soil, water, and air samples to isolate contaminants such as pesticides, phenols, or acidic herbicides.
Food and Beverage Testing:
Removing fats, pigments, or organic acids from food matrices before quantification of target analytes (e.g., preservatives, toxins).
Sample prep for drugs of abuse, acidic metabolites, and other trace-level components in biological samples.
Features of AL-N (Neutral Alumina) Phase:
Polar sorbent that interacts with analytes via hydrogen bonding, dipole-dipole, and ionic interactions.
Neutral alumina helps in selective retention of certain compound classes, especially acidic ones.
Often used in normal-phase SPE methods (as opposed to reversed-phase).
