Ultimasyil AQ HPLC Columns – 100 Å Pore Size:
A 100 Å (10 nm) pore size is standard for many reversed-phase HPLC columns designed for small-molecule separations. For an Ultimasyil AQ (often meaning “aqueous-compatible” or “AQ-endcapped”) column, the 100 Å version is generally used for:
Ideal for compounds with molecular weights up to ~2 kDa, including:
Pharmaceuticals and APIs
Impurities and degradants
Metabolites
Environmental contaminants
Organic acids and basic/neutral small molecules
“AQ” phases are engineered to be stable in high-water content mobile phases, preventing phase collapse. Suitable for:
Hydrophilic or polar analytes
Gradient elution starting at high aqueous percentage