National Chromatography Inco
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The ULTIMASYIL C8 – 150 Å column is specifically developed for the reversed-phase separation of larger molecules such as peptides, small proteins, and other mid-to-high molecular weight compounds. With a 150 Å pore size, this column provides improved mass transfer and enhanced interaction with larger analytes, while maintaining excellent peak shape and resolution.
Key Features:
Stationary Phase: Octylsilane (C8) bonded to ultra-pure, high surface area silica
Pore Size: 150 Å – optimal for biomolecules and larger organic compounds
Particle Sizes: 3 µm, 5 µm
End-Capped: Yes – minimizes silanol activity and ensures sharp, symmetrical peaks
Compatibility: Suitable for a wide range of organic solvents and buffer systems
Performance Benefits:
Faster elution than C18 with sufficient retention for moderately non-polar compounds
Enhanced accessibility for large molecules due to wider pores
High mechanical and pH stability for reproducible results
Suitable for both analytical and semi-preparative scale workflows
Typical Applications:
Peptides and peptide-related impurities
Biopharmaceutical intermediate analysis
Complex formulation profiling
Natural product and plant extract separations
The ULTIMASYIL C8 – 150 Å column offers a smart balance of retention and efficiency for large molecule separations, making it an excellent choice for pharmaceutical, biotech, and life science research.
